Piazza Duomo 37 Bed & Breakfast Comacchio is situated about 5 minutes' drive from La Manifattura dei Marinati Local History Museum, which is an excellent place to improve cultural awareness. A car park is available nearby at the bed & breakfast.

Clock Tower of Comacchio stands a 16-minute walk away, and Basilica San Cassiano is just a minute's drive from this property. From the hotel it will take 18 minutes to walk to Trepponti. The accommodation allows you to enjoy such natural sights as Po Delta Interregional Park a 5-minute ride away. Piazza Duomo 37 Bed & Breakfast is located 75 km from Guglielmo Marconi airport and at a 950-metre distance from Comacchio Ospedale bus stop.

Bathrooms with a bidet, a bathtub, and a separate toilet, also include a hairdryer and bath sheets.

The café Bar Ragno is just 1.3 km away.